Palestinian residents have reported heavy strikes across Gaza City and Israel's defense minister has said "Gaza is burning."

An Israeli army flare drifts over buildings destroyed during the Israeli ground and air operations in the northern Gaza Strip, as seen from southern Israel, Monday, Sept. 15, 2025. (AP Photo/Leo Correa)

Palestinian residents reported heavy strikes Tuesday across Gaza City as Israel’s defense minister said that “Gaza is burning,” in remarks that come as Israel has been planning a new offensive targeting the city.

U.S. Secretary of State Marco Rubio, speaking to journalists while leaving Israel for Qatar, suggested the offensive had begun.

Overnight strikes in Gaza City killed at least 12 Palestinians, including two children, according to Shifa Hospital, which the received the bodies.

“It was a heavy night,” said Radwan Hayder, a Gaza City resident sheltering near the hospital.

Here's the latest:

Israeli strike kills at least 12 Palestinians in Gaza City, hospital says

Shifa Hospital in Gaza City received the bodies of 12 people who were killed in a strike that hit multiple houses in the western part of the city, said Dr. Rami Mhanna, managing director of the hospital.

He told The Associated Press that more than 90 injured also arrived at the facility in the past six hours.

He said first responders reported that many casualties are still under the rubble in multiple areas, and that the death toll is likely to increase.

Rubio says time running out for negotiated settlement

U.S. Secretary of State Marco Rubio, speaking to journalists while leaving Israel for Qatar, acknowledged the start of operations in Gaza City and stressed the need for an immediate end to the conflict that eliminates Hamas.

“The Israelis have begun to take operations there. So we think we have a very short window of time in which a deal can happen,” Rubio said. “We don’t have months anymore, and we probably have days and maybe a few weeks to go.”

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Smoke rises to the sky following an Israeli military strike in the Gaza Strip, as seen from southern Israel, Monday, Sept. 15, 2025. (AP Photo/Leo Correa)

Rubio said a deal would need to include the release of hostages and the demilitarization and disarming of Hamas.

Rubio plans to visit Qatar on Tuesday after meeting with Israeli Prime Minister Benjamin Netanyahu a day earlier in Israel, where they showed a unified front in the face of international anger over Israel’s airstrikes on Hamas leaders in Qatar and its bombardment of Gaza City.

The Trump administration appears keen to ease tensions between its two close allies, following Israel’s strike in Doha last week.

Displaced Palestinians flee northern Gaza by foot and in vehicles, carrying their belongings along the coastal road toward southern Gaza, Monday, Sept. 15, 2025. (AP Photo/Abdel Kareem Hana)